Bio 181, Fall 2005

Dr. Lisa Werner

 

Learning Objectives for Chapter 8, Energy

 

Understand and be able to use the following terms:

 

metabolism

metabolic pathwy

anabolism

catabolism

thermodynamics

energy

kinetic energy

potential energy

kilocalorie

joule

chemical energy

 ∆G

heat

entropy

free energy

enthalpy

endergonic

exergonic

equilibrium

ATP

ADP

enzyme

catalysis

catalyst

activation energy

substrate

enzyme-substrate complex

inhibitor

activator

cofactor

coenzyme

allosteric regulation

feedback inhibition

multienzyme complex

 

 

 

 

1.       Define metabolism.

2.       Give a brief explanation of what a metabolic pathway is.

3.       What is energy? Distinguish between kinetic and potential energy, and give examples of each.  What are the units for energy?

4.       Be able to give the two laws of thermodynamics and explain how they relate to energy in living organisms.

5.       Define Gibbs Free energy, and be able to explain what ∆G = ∆ H – T∆ S means.

6.       Explain the relationship of free energy to stability, work capacity, and spontaneous change

7.       Distinguish between endergonic and exergonic reactions.  Be able to discuss the role of free energy in determining whether a reaction is endergonic or exergonic.

8.       Describe the relationship between equilibrium and metabolism, explaining why it is important that a cell is an open system.

9.       Describe the structure of an ATP molecule and state where the energy is stored.

10.    Explain how ATP powers energy requiring reactions.

11.    Describe the properties of enzymes, and their role in metabolism.

12.    Define activation energy, and explain the role of activation energy and catalysts in determining the rate of a reaction.  Will lowering the activation energy allow an endergonic reaction to proceed?  Explain.

13.    Explain how enzymes work.

14.    What factors influence enzyme activity?  Explain how each influences activity.  What is a temperature or a pH optimum?  Distinguish between competitive and non-competitive inhibitors.  What is an allosteric site?  Give some examples of cofactors and coenzymes.

15.    Give examples of how cellular structures can organize metabolic pathways.